What Corvalol helps from: indications for use, composition, mechanism of action and side effects. Is it possible to combine Corvalol and alcohol Is it possible to drink Corvalol with tablets from

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“Something pressed down in the chest”, “you need to calm down”, “something is hard to breathe” - this is how people motivate their decision to use a few drops of Corvalol. And many are accustomed to consider this drug to be quite safe - it will certainly be found in every medicine cabinet. But what is Corvalol really, who can take it, and to whom is it categorically contraindicated? These questions can only be answered by experts.

Table of contents: Corvalol - instructions for use The composition of Corvalol How Corvalol works Corvalol - indications for use Corvalol - contraindications How to take Corvalol Side effects Overdose Interaction of Corvalol with other drugs Is Corvalol harmful

Corvalol - instructions for use

Before taking any drug, you need to carefully read the official annotation to it. But who reads these instructions? But even Corvalol, at first glance, an absolutely safe drug, has its own indications and contraindications, and can provoke the development of side effects.

Composition of Corvalol

The drug in question is produced in the form of drops and tablets, but Corvalol drops are especially popular. They include:

ethyl bromoisovalerianate;
peppermint oil;
phenobarbital;
sodium hydroxide;
purified water;
ethanol.

The appearance of Corvalol drops is a clear liquid, without any tint impurities. It has a specific pleasant aroma.

How does Corvalol work?

The drug in question belongs to the group of combined ones, but all the components included in its composition are optimally combined with each other, correcting the action of each.

Ethylbromisovalerianate has a sedative and antispasmodic effect. Phenobarbital, in turn, enhances the sedative effect of ethyl bromisovalerianate, actively helps to reduce the excitability and tension of the central nervous system, and makes calm sleep onset possible. And peppermint oil has a complex effect on the human body: antispasmodic, choleretic, vasodilating, antiseptic. Therefore, peppermint oil contributes to the expansion of the vessels of the heart and brain, irritates the mucous membrane of the organs of the gastrointestinal tract - this restores intestinal motility and helps to cope with increased gas formation.

Corvalol - indications for use

There is a clear designation of those conditions in which it is advisable to use Corvalol. These include:

Neurosis-like states - increased irritability, unmotivated outbursts of anger, depressed mood, a feeling of anxiety.
Functional disorders of the cardiovascular system - Corvalol is especially often recommended for people with diagnosed angina pectoris, arrhythmia, tachycardia.
Intestinal spasms - for example, with intestinal dysbacteriosis, diarrhea against the background of food poisoning.
Sleep disturbances - insomnia at night and drowsiness during the day, problems with falling asleep, frequent awakening.

Corvalol - contraindications

The drug in question is not used in pediatric practice, at least for children under 3 years of age it cannot be clearly prescribed. In older children, the question of the advisability of prescribing and using Corvalol should be decided only by a doctor.

No studies have been conducted on the effect of Corvalol on the body of a pregnant woman, during breastfeeding and on the intrauterine development of the fetus. Therefore, it is forbidden for a woman to take the drug in question during these periods of her life.

It is strictly forbidden to use Corvalol in case of a traumatic brain injury, some diseases of the brain (the attending physician should warn about this), and diagnosed alcoholism.

It is not recommended to use the drug in question in violation of the functions of the liver and kidneys of a severe nature of the course - for example, with renal failure, cirrhosis of the liver. But this issue is decided on a strictly individual basis.

How to take corvalol

The dosage that will have the expected effect and will not harm the general state of health should be determined only by a specialist and on an individual basis. But in the instructions for the use of Corvalol there are also general recommendations for its use:

adults can take 30 drops per dose, in case of diagnosing tachycardia and with the approval of a doctor, the dosage can be increased to 40 drops per dose. Corvalol can be consumed 2-3 times a day;
children over 3 years of age are prescribed 1 drop for each year of life once a day. In some cases, repeated administration of Corvalol is allowed, but the doctor must give permission for this.

The duration of the course of treatment is determined only by the doctor and it is strictly forbidden to independently prolong it (“to consolidate the effect”).

Side effects

Despite the seeming simplicity and safety, Corvalol can in some cases cause side effects. These include:

increased drowsiness;
constant dizziness;
the level of concentration of attention decreases;
heart rate slows down.

Note: if corvalol is taken for a long time, then the so-called bromism phenomena may develop - addiction and drug dependence, the “withdrawal” syndrome.

If the above side effects (or at least one of them) appear, you should immediately stop taking Corvalol and seek medical advice. Most likely, a correction of the treatment regimen will be carried out or the dosage of the drug in question will be reduced.

Overdose

Cases of overdose with Corvalol are extremely rare, but can occur. Therefore, everyone who uses the drug in question needs to know the first signs of an overdose. These include:

lowering blood pressure;
nystagmus;
depression of the central nervous system - apathy, clouding of consciousness;
rhinitis;
hemorrhagic diathesis;
ataxia;
movement coordination disorders.

If at least one sign of an overdose appears, the use of the agent in question should be stopped immediately and medical professionals should be consulted for help. Usually, doctors prescribe symptomatic therapy for an overdose of Corvalol, and if signs of depression of the central nervous system are already observed, then caffeine and nikethamide.

Interaction of Corvalol with other drugs

It is strictly forbidden to use the drug in question if any sedatives are already being taken - they enhance the effect of each other, which can lead to an overdose.

Please note: in Corvalol contains phenobarbital and ethyl alcohol - these are substances that can affect the central nervous system. Therefore, when taking the agent in question, it is not recommended to drive vehicles, to conduct labor activities associated with the need for a high concentration of attention.

Is corvalol harmful

The debate about how dangerous Corvalol is for human health has been relatively recent. Some time ago, many thought that Corvalol would be banned for sale in the Russian Federation - it contains both phenobarbital and ethyl alcohol. But it turned out to be just rumors - such combined drugs remain on the free market.

However, in most countries, Corvalol cannot be found in pharmacy chains - it was withdrawn from sale without prescriptions. For example, the USA, Great Britain, Norway, Italy, the United Arab Emirates, Poland, Finland and Sweden have not only banned Corvalol for free sale, but also strictly control the transport of this drug across the border into their countries. Therefore, be extremely careful - if possible, then when visiting the listed countries, replace the drug, if this is not possible, the doctor prescribes it, then take care of having a document confirming this fact. Otherwise, punishment will follow under the laws of a particular country.

“So far, our population has a very strong habit of using this drug. Radical measures - a ban on the sale of Corvalol, its withdrawal from consumption - will cause a negative reaction from patients. At the same time, Corvalol will gradually be replaced by other, more modern drugs with proven effectiveness.

Why is Corvalol so dangerous?

Firstly, phenobarbital, which is part of the drug in question, has been included in the group of psychotropic drugs since 2013. In fairness, it needs to be clarified - in many countries of the world, such a classification of phenobarbital has been accepted for a very long time.

Secondly, it is phenobarbital that causes rapid and strong addiction - in some cases, 2-3 weeks of taking the drug is enough for the development of drug dependence. Moreover, phenobarbital causes not only physical, but also psychological dependence.

Thirdly, after the abolition of Corvalol, people develop the so-called "withdrawal" syndrome - a depressed state, the patient complains of constant nausea, intense headaches.

Interesting fact: phenobarbital is used in some countries to carry out the death penalty.

But isn't there anything useful in the tool in question? Indeed, for a long time, Corvalol was recommended for use by millions of patients, and in most cases, the course of therapy with the drug in question did not cause any consequences. Corvalol has one indisputable advantage - it has the fastest and most powerful effect.

If taken in small doses and extremely moderately, then Corvalol can quickly, almost instantly, relieve anxiety. In general, the recommended doses of the remedy are not dangerous, but the problem is that if you take it constantly, then there is a need to increase the dosage. The most dangerous thing is that these doses do not just increase each time, but lead to real pleasure: depression and dizziness are replaced by euphoria immediately after taking the right dose.

The popularity of Corvalol is due to the fact that it is a cheap drug that has been known to everyone for a long time and has a quick effect, but it should be used only when absolutely necessary or as directed by a specialist. If a person feels the manifestations of the side effects listed in this article, or others notice sudden mood swings in someone who periodically uses Corvalol, then you should urgently seek medical help. The fact is that drug dependence should be treated only in specific medical institutions.

Tsygankova Yana Alexandrovna, medical observer, therapist of the highest qualification category

Corvalol is a sedative popular in the countries of the former USSR, but banned in Poland, Germany, the USA, Norway, and Lithuania. Prohibitive measures were taken due to the presence of the psychoactive compound phenobarbital in the composition of Corvalol, as well as the toxic bromine-containing component.

What makes the drug popular with Russians who drink an average of 40 railway tanks of medicine a year? And today we will talk in more detail about the indications and instructions for the use of Corvalol drops and tablets, its price, reviews, composition, analogues.

Features of the drug

The combined drug Corvalol exhibits a sedative, vasodilating effect, is used against insomnia, as a sedative for stress, emotional stress. The Ministry of Health of the Russian Federation recognized Corvalol as a drug with a low content of a psychoactive substance, allowed it to be sold without a prescription, and plans to refuse to prescribe this drug to patients in the future, replacing it with more modern drugs.

When using Corvalol, it must be remembered that this remedy does not cure diseases of the heart, nervous system, but only eliminates the manifestations of the disease.

This video will tell about the dangers and benefits of Corvalol:

Composition of Corvalol

The active ingredients of the drug Corvalol:

ethyl ester of alpha-bromovaleric acid (ethyl bromoisovalerianate);
phenobarbital;
peppermint leaf oil.

Auxiliary substances of Corvalol in drops are:

ethanol;
sodium hydroxide;
purified water.

Auxiliary components in tablets - betadex, lactose, potato starch, magnesium salts.

Dosage forms

Corvalol is produced in alcohol drops, tablets for resorption sublingually (under the tongue). Tablets are packed in blisters of 10, 30 and 50 pieces.

Alcohol drops are packaged in dark glass bottles with a capacity of 15 ml, 25 ml, 50 ml. Alcohol tincture has a strong specific aroma. The average price of Corvalol tincture is:

for a container of 15 ml - 16 rubles;
25 ml - 23 rubles;
50 ml - 33 rubles.

Prices for Corvalol can vary between 9 - 120 rubles. The cost of 10 Corvalol tablets is 18 rubles.

pharmachologic effect

Corvalol belongs to the group of sedatives, is a combination drug that exhibits a calming, antispasmodic, vasodilating effect, contributing to the normalization of sleep.

The video below will talk about both the composition and the properties of Corvalol:

Pharmacodynamics

The properties of Corvalol are determined by the total effect of its active components.

The main active ingredient is ethyl bromisovalerianate. This compound eliminates the spasm of the smooth muscles of the internal organs, calms, relaxes the nervous system.
Phenobarbital has the ability to act on the central nervous system, directly removing the excitation of the nerve centers of the brain. The sedative effect of phenobarbital is less pronounced.
Peppermint oil, irritating the "cold" sensitive nerve endings of the oral cavity, selectively expands the vessels of the brain, coronary vessels that feed the heart muscle. The oil exhibits choleretic, antiseptic activity, helps to eliminate flatulence.

Pharmacokinetics

The action of the drug in tablets begins in the oral cavity. The positive effect of the drug on the patient's well-being when the tablet is resorbed under the tongue appears almost instantly.

The effect of Corvalol when taken in the form of drops is noticeable after 10-30 minutes. The duration of action of the drug when taken in tablets and drops is 6 hours.

Of the active ingredients of Corvalol, the pharmacokinetics of phenobarbital has been most studied. This compound is well absorbed, has the ability to accumulate in the body. The half-life of phenobarbital is 2-4 days. The compound is decomposed into simple components in the liver, excreted by the kidneys in the form of a glucuronide, partially (25%) unchanged.

In old age, with impaired liver function, the half-life of the drug from the body is lengthened. This requires correction of the dosage of the drug in the direction of decreasing, increasing the intervals between doses of the medication.

What helps Corvalol, how to take it, we will tell further.

Indications

Functional disorders of the cardiovascular system;
sleep disorders;
neurosis-like states;
the initial stages of hypertension, spasms of the vessels of the heart;
tachycardia;
spasms of the intestines.

Instructions for use

For adults, Corvalol tablets are prescribed 1 tablet for an attack of tachycardia, spasms of blood vessels. If necessary, the dosage of the drug can be increased to 3 tablets.
Alcohol tincture of Corvalol is taken with water, 10-30 drops or on a piece of sugar. The maximum single intake of tincture should not exceed 50 drops.

The treatment regimen is chosen by the doctor individually. The drug is taken no more than 3 times a day, the duration of the course of treatment depends on the patient's condition, the dynamics of the disease.

According to the instructions, Corvalol is not allowed to be used for treatment earlier than 18 years. In acute situations, the doctor may prescribe the child to take the drug at the rate of 1 drop for each year of age.

You can give medicine to children no more than once a day, in the amount of 3-15 drops. Treatment should be supervised by a doctor due to the lack of data on the effect of Corvalol on the children's body.

Contraindications

Hypersensitivity to the components of the drug;
age up to 18 years;
pregnancy, lactation;
lactose intolerance;
heart disease;
renal, liver failure.

Corvalol is not allowed during pregnancy due to the ability of its phenobarbital component to penetrate the placental barrier and have a teratogenic effect on the fetus. Taking medication during pregnancy can provoke the appearance of congenital anatomical deformities, a violation of the formation of internal organs.

Side effects

The most dangerous side effect of Corvalol is psychological addiction to phenobarbital. And, if the physical dependence on phenobarbital is weakly expressed, then the mental dependence is formed quickly.

Mental dependence makes you take the treasured vial with you everywhere, in all difficult situations, resort to its magical calming effect, simultaneously increasing the concentration of bromine contained in ethyl bromisovalerianate in the body.

Signs of bromine poisoning are:

inhibition of the functions of the central nervous system;
tendency to depression;
confusion;
lack of coordination.

Taking Corvalol can cause side effects from:

nervous system - inability to concentrate, dizziness, drowsiness;
cardiovascular system - bradycardia;
digestive system - nausea, vomiting, stomach pain.

special instructions

The drug should not be combined with the use of alcohol, mainly due to the presence of phenobarbital in its composition. This component is destroyed in the liver, like alcohol, which leads to an increased load on it.

Phenobarbital, which is part of Corvalol, has the property of enhancing the effect of sedatives. Corvalol is combined with caution with sleeping pills, analgesic drugs, it is not recommended to drink the drug with drugs that metabolize in the liver - hormonal drugs, antibiotics, contraceptives.

Overdose

Exceeding the dose of Corvalol is accompanied by a drop in blood pressure, dizziness, and inhibition of brain activity. If the symptoms of an overdose of Corvalol do not disappear after discontinuation of the drug, the patient's stomach is washed, and an ambulance is called.

In severe conditions, it is possible:

neuromuscular violation of the coordination of muscle work - ataxia;
violation of the rhythm of heart contractions, increased heart rate;
a sharp drop in blood pressure;
loss of consciousness, coma.

Prolonged use of the drug can cause dependence, and if treatment with Corvalol is canceled, it can cause a withdrawal syndrome.

Reviews

More than 90% of consumers who have resorted to treatment with Corvalol note its calming effect on the nervous system, the ability to normalize sleep, and calm a strong heartbeat.
Among the negative reviews, there is the presence of alcohol in the composition of the drops, the possibility of addiction to phenobarbital and ethyl alcohol. The reality of this threat is manifested in the gradual increase in the dose of the drug.
Almost always, starting with a small dose of 10-15 drops, patients gradually increase a single dose of Corvalol to 60 drops, which indicates an increase in tolerance to the drug and indicates the formation of a real drug addiction.

Analogues

Analogues of Corvalol include Valocordin, Valecard-Health, Corvaldin, Reladorm.

This video will tell about the narcological properties of Corvalol:

A drug that has a complex effect on the body, sedative (calming), vasodilating and antispasmodic, is Corvalol. Instructions for use marks it as a remedy that helps to alleviate a person's condition in case of sudden heart problems that occur against the background of a disorder of the nervous system and stress.

Release form

Corvalol is available in the form of drops in dropper bottles of 15 ml, 25 ml and 50 ml, and round white or almost white tablets of 10, 30, 50 pieces per pack.

Drops include:

ethyl ester of alpha-bromoisovaleric acid - 2%;
phenobarbital - about 2%;
mint oil - 1.14%.

Auxiliary components:

caustic soda (sodium hydroxide);
alcohol-water mixture - ethyl alcohol and distilled water.

The composition of 1 tablet includes:

ethyl ester of alphabromisiovaleric acid - 8.2 mg;
phenobarbital - 7.5 mg;
peppermint oil - 0.58 mg.

Auxiliary components in tablets:

beta-cyclodextrin - 55.6 mg;
potato starch - 13 mg;
lactose monohydrate - 43.8 mg;
microcrystalline cellulose - 10.5 mg,
magnesium stearate - 0.9 mg.

Pharmacological properties and action of the drug

The main effect of the drug is aimed at reducing the processes of excitation in the central nervous system, eliminating muscle spasms on the walls of blood vessels, and facilitating falling asleep. Therefore, the drug is mainly used for functional disorders of the nervous and cardiovascular systems. As part of complex therapy, Corvalol can be used as an adjuvant for various diseases of the heart, blood vessels, and gastrointestinal tract.

The pharmacological properties of Corvalol depend on the active substances that make up its composition:

Ethyl ester of alpha-bromoisovaleric acid, in addition to a calming effect, relieves spasms of the smooth muscles of blood vessels and internal organs.
Phenobarbital has a hypnotic effect. In the minimum dosage, it acts as a mild sedative, slightly dilating the blood vessels.
Peppermint oil, acting on certain receptors, dilates blood vessels and even has a choleretic effect. It is a mild anti-inflammatory and antispasmodic.

Indications for use

At present, filled with stressful situations, the primary medicine that is present in every home is Corvalol. Indications for the use of this sedative are as follows:

irritability;
vegetative lability;
insomnia;
hypochondriacal syndrome;
nervous disorders of a functional nature.

As a vasodilator, the drug is used in complex therapy for:

atherosclerosis;
cardialgia;
sinus tachycardia;
ischemic heart disease;
arterial hypertension.

The antispasmodic properties of this remedy help with:

vegetative-vascular dystonia,
diseases of the digestive system, accompanied by spasms (intestinal and biliary colic).

How to use

Adults take Corvalol half an hour before meals, 15-30 drops diluted in a small amount (50 ml) of water. The same number of drops can be applied to a piece of sugar and taken as such 2-3 times a day. If the cause of concern is associated with a strong heartbeat (tachycardia), then you can increase the dosage by taking 40-50 drops.

Tablets are taken orally 1-2 pieces 2-3 times a day with water or sublingually (under the tongue). With tachycardia, you can use 3 tablets at a time.

When taking the drug sublingually, its absorption begins in the sublingual region and the positive effect appears almost instantly.

The period of use of the drug is determined by the doctor, based on the data of the clinical effect and individual tolerability of the drug.

Corvalol for children

Physicians do not have a single opinion on this matter. Some doctors believe that children can be given from 3 to 15 drops per day, but only on the advice of the attending physician.

Others argue that Corvalol is not prescribed for children under 18 years of age.

special instructions

During the use of Corvalol, alcohol is prohibited.

This drug is well tolerated by most people, but it is not recommended to take it for a long time, due to a decrease in the therapeutic effect when addictive, and at high doses in combination with long-term use, drug dependence may occur, which, when stopped, can cause a withdrawal syndrome.

It should also be borne in mind that the combined use of the drug with other drugs with a calming effect significantly enhances its effect.

The drug should be taken with caution in case of arterial hypotension.

Pregnancy and lactation

When breastfeeding a child, the medication is prohibited, but if a decision is made in favor of the use of Corvalol, then it is necessary to abandon breastfeeding for this period.

During pregnancy, the drug is contraindicated. If necessary, and in agreement with the attending physician, you can use soothing herbal teas or medicines such as Novo-Passit or Persen.

Contraindications

This sedative should not be taken in severe hepatic and renal insufficiency, glucose-galactose malabsorption, lactose intolerance, hypersensitivity to its components, pregnant women and nursing mothers (see above).

Interaction with other medicines:

the effect of Corvalol is enhanced by drugs of a central inhibitory type of action;
the main active ingredient phenobarbital increases the activity of liver enzymes, and therefore the simultaneous use of Corvalol with drugs undergoing biochemical transformations in the liver (for example, oral contraceptives, griseofulvins, drugs with coumarin derivatives, GCS) is not desirable;
the described remedy can enhance the effect of taking sleeping pills and painkillers (due to the content of barbituric acid derivatives in Corvalol);
Corvalol enhances the effects of Valproic acid (an anticonvulsant);
when taking Corvalol together with the antitumor drug Methotrexate, its toxicity increases;
alcohol increases the toxicity of the drug and enhances its effect.

Side effects and overdose

The drug is well tolerated by most people, but negative reactions from the body still occur when taking Corvalol. Instructions for use indicate that there may be slight dizziness, decreased concentration, a feeling of drowsiness, short-term diarrhea, skin allergies.

But the excessive use of the drug (overdose) can cause serious harm to health. The fact is that Corvalol contains a bromine-containing substance, which, with frequent use of the drug, causes the accumulation of bromine in the body and the corresponding symptoms: lethargy, depression, lacrimation, impaired motor coordination, rhinitis, conjunctivitis. Symptoms of an overdose include: depression of the central nervous system, nystagmus (oscillatory eye movements with high frequency), ataxia (dysmotility), lowering blood pressure, agitation, dizziness, weakness.

If symptoms of an overdose occur, it is necessary to stop taking the drug, rinse the stomach, further treatment is symptomatic.

How to replace Corvalol - analogues

Analogues of the drug according to the mechanism of action include:

Adonis bromine;
Barboval;
Valecard-health;
Valemidin;
Valocordin;
Valoserdin;
Darvilol;
Drops of lily of the valley-valerian;
Drops of lily of the valley-motherwort;
Corvaldin;
Corvaltab;
tincture of Hawthorn;
motherwort tincture
Reladorm.

Structural analogues for the active substance: Corvalol-MFF.

Storage conditions and shelf life

It is necessary to store drug in the place, unavailable to children, protected from light, at a temperature from 15 to 25 °C.
Shelf life - 2.5 years, it must be indicated on the label. After the expiration date, the medicine can not be taken.
It is released in pharmacies without a prescription.

Corvalol is a sedative proven over the years that suppresses stress, nervousness, and excitement. With proper application, it will always help to survive the hardships of modern life. Be healthy!

Medication "Corvalol" (indications for the use of this tool will be discussed a little later) is a sedative, sedative drug. You will learn about the conditions under which it should be used, and other information from the materials of the presented article.

The composition of the drug

This tool is made on the basis of ethyl ester of alpha-bromoisovaleric acid, menthol and phenobarbital. As for excipients, they include the following: beta-cyclodextrin, potato starch, tabletose, magnesium stearate and microcrystalline cellulose.

Release form

What is the drug "Corvalol" prescribed for? Indications for the use of this tool, its principle of action and side effects will be described in detail in the following sections of the article. Now it will be told about the forms in which this tool is produced. In pharmacy chains, the medicine "Corvalol" can be purchased in the form of drops. In addition, this drug is sold in tablets for oral and sublingual use.

pharmachologic effect

The drug "Corvalol" is a combined drug, the action of which is determined by the properties of its constituent components. It has a reflex vasodilating (that is, dilates blood vessels), antispasmodic and calming effect, and also greatly improves the natural onset of sleep. To understand how the presented medication works, consider the pharmacodynamics of its active components:

Phenobarbital facilitates the onset of sleep, significantly enhances the sedative effect of other substances and helps to reduce the excitability of the central nervous system.
The ethyl ester of alpha-bromoisovaleric acid, like the effect of valerian, has an antispasmodic and sedative effect.
Peppermint oil has an antispasmodic and reflex-vasodilating effect.

Physical properties of the drug

The drug "Corvalol" in the form of drops is available in dark glass jars with a dispenser nozzle, inside which there is a transparent colorless liquid in the amount of 25, 30 or 50 ml with a specific odor. As for a similar medication, but only in the form of white tablets, it is placed in a carton of 20 pieces.

The drug "Corvalol": indications for use

This drug is used as a vasodilator, sedative and antispasmodic in the following pathological conditions:

insomnia or disturbances in the process of falling asleep;
hypochondriacal syndrome;
disorders of the cardiovascular system (for example, with such deviations as sinus tachycardia, cardialgia and high blood pressure);
vegetative lability;
spasms of the muscles of the digestive tract (for example, with biliary and intestinal colic);
neurotic states;
irritability.

Contraindications to the use of the drug

According to the instructions, the drug "Corvalol" is not recommended for use with such deviations as severe hepatic and renal failure, during lactation and with increased sensitivity to the active ingredients of the drug.

Instructions for use of the drug

Calming medication "Corvalol" should be taken orally before meals in the amount of 15-30 drops three times a day. Before direct use, this drug must be dissolved in 30-50 ml of ordinary drinking water. According to the instructions, a single dose of such a remedy for vascular spasms and tachycardia can be increased to 30-40 drops. Medication "Corvalol" for children is usually prescribed in the amount of 3-15 drops per 3 large tablespoons of cooled boiling water. The duration of treatment with this drug in each individual case is determined individually and only by the attending physician. As for the drug in tablets, it should be taken 1 or 2 pieces before eating three times a day. With tachycardia, this drug is allowed to be taken in the amount of 3 pieces at a time.

Use with caution

This tool should be used with extreme caution in the following cases:

during the period of bearing a child;
while driving;
when managing any mechanisms;
during activities that require concentration and reaction time.

Other uses

Very many representatives of the fair sex use the drug "Corvalol" for acne. To do this, moisten a cotton pad in the medicine, and then wipe the affected skin. Due to the fact that the product contains essential oils, it helps to reduce inflammation and kill existing bacteria. After such treatment, you must wait until the medicine is completely absorbed, and then apply a soft and moisturizing cream to the skin.

Side effects

The use of the drug "Corvalol" in some patients can cause a decrease in heart rate, dizziness, allergic reactions, drowsiness and loss of concentration. Long-term therapy with this drug (especially in large doses) quite often leads to addiction, bromism, dependence and "withdrawal" syndrome.

drug overdose

If you exceed the prescribed dose of this remedy, then the patient may experience symptoms of depression of the nervous system. In addition, an overdose of Corvalol threatens with a decrease in blood pressure, ataxia, nystagmus, chronic bromine poisoning, as well as rhinitis, hemorrhagic diathesis, depression, impaired motor coordination, apathy and the appearance of conjunctivitis. In such cases, the patient is prescribed symptomatic therapy. When the nervous system is depressed, "Caffeine" and "Niketamide" are prescribed.

Popularity of the remedy

Due to its availability and low cost, the drug "Corvalol" (indications for use were described above) is actively used as an anti-anxiety and sedative. Very often it is prescribed to patients with depressive disorders. But with regular use in high doses, such a medication can cause serious cognitive and neurological impairment (for example, a short-term memory disorder, unsteady gait, speech impairment, etc.), as well as suppress sexual function. Pharmacy remedy "Corvalol" causes withdrawal and tolerance. In such cases, the patient must be referred to a psychiatrist and narcologist. In medical practice, there were situations when a patient was hospitalized in the toxicology department with phenobarbital poisoning (when taking 125 ml of the drug for 3 days).

General information about the drug

The drug "Corvalol" is practically unknown and is not used outside the countries of the former USSR and Eastern Europe. However, in some Western European countries, its German counterpart Valocordin is available to consumers. It should be especially noted that in individual countries, the active components of this drug are classified as drugs that are prohibited for sale and import. In particular, the drug "Corvalol" is strictly prohibited from being transported to the United States of America and Lithuania. In Poland, there is a similar remedy "Milocardin", with phenobarbital included in it. In accordance with Decree No. 681 of the Government of the Russian Federation of June 30, 1998, this component is included in the list of psychotropic substances. As you know, their circulation in our country is limited.

To relieve heart pain that occurs with excessive action of a traumatic factor or a violation of the hormonal regulation of the body, insomnia, a drug such as Corvalol is prescribed. It is used for the complex treatment of hypertension, vegetovascular dystonia, mild spasm of the coronary arteries of the heart.

With a painful attack and increased heart rate, a single dose can be increased to 40 or 50 drops. It should be noted that for elderly patients and in case of impaired liver function, the excretion of the drug is impaired, so the daily dose should not exceed 50-60 drops.

With prolonged use, accumulation of Corvalol in the tissues is possible, which leads to toxic effects. Therefore, the drug is not recommended for permanent use, and the attending physician should prescribe the exact dose and duration of the course of therapy.

Restrictions on taking Corvalol

The drug is not prescribed for children under 18 years of age, during pregnancy and lactation.

Side effects of Corvalol

Long-term therapy with Corvalol leads to the development of dependence on the drug, with its abrupt withdrawal, an abstinence syndrome with motor agitation and increased irritability is possible.

High doses cause intoxication, which is manifested by such clinical symptoms:

suppression of breathing, up to a complete stop;
coma;
violation of the heart rhythm by the type of bradycardia;
drop in blood pressure, ;
low body temperature;
decrease in urine output.

When treating with Corvalol, you should not take alcoholic beverages, drive a car, work in production with mechanisms that require a quick motor reaction or increased concentration of attention. With the simultaneous use of drugs such as Aspirin, Indomethacin, Diclofenac, the risk of ulcerative lesions of the gastric mucosa increases.

Validol or Corvalol for pain in the heart - what to choose?

The use of Validol and Corvalol is indicated for pain in the heart, which is not associated with blockage of the coronary vessels, inflammatory or degenerative processes in the myocardium. With these diseases, taking such drugs will not have a therapeutic effect.

If an attack of pain lasts more than 30 - 40 minutes and its intensity does not decrease, then you need to urgently call an ambulance. Before she arrives, you can take an aspirin tablet and 2 nitroglycerin tablets at intervals of 15 minutes. With increased pressure, take 1 tablet.

For pains in the heart that are associated with neurosis or stress, sedative drugs are prescribed, which include Corvalol. Its reception relieves vasospasm and causes inhibition processes in the cerebral cortex. Uncontrolled use is not recommended without a doctor's recommendation. Contraindicated in violation of the function of the liver, kidneys, drug or alcohol dependence. Large doses cause poisoning.

If there is no effect from taking it during an attack of heart pain, you should urgently consult a doctor to exclude an acute violation of the blood supply to the myocardium.

Reviews about "Corvalol (drops)" from doctors and patients:

Previously, there was opium for the people, now it is Corvalol. Let me explain the analogy. A truly massive and super popular Corvalol was invented in Germany (more precisely, its almost complete analogue of valocordin). They filmed the post-war depression in the 50s. the last century.

Why do I care? Yes, because my elderly relatives drink Corvalol and everyone considers it harmless droplets. Well, who does not know Corvalol, its smell, taste? Meanwhile, in our country, not a single normal study has been conducted on the effect of this drug on the health of the elderly. It is known that rats treated with phenobarbital throughout their lives died of cancer. The symptoms of chronic intoxication are also known: drowsiness, irritability, weakness, confusion, hallucinations, convulsions, imbalance, as well as changes in the work of the cardiovascular, digestive and urinary systems.

Now think about why my grandmother had dementia (senile dementia) so early, and my grandfather died of cancer.

Corvalol: instructions for use

Application of Corvalol

Corvalol is a combination drug that contains phenobarbital, peppermint oil, water, ethyl alcohol and ethyl ether. Thanks to phenobarbital, which has a vasodilating effect, peppermint oil works more effectively, reducing spasm and dilating blood vessels. When the dose is increased, Corvalol acts as a hypnotic. The drug is used for neuroses of various origins with pain in the heart and increased irritability, with angina pectoris, intestinal cramps, palpitations, hypertension. Corvalol is well tolerated and only occasionally can cause slight dizziness and drowsiness.

Drops Corvalol: dosage

As such, the dosage of Corvalol does not exist. In the form of drops, the drug is available in 25 ml vials. They should be taken before meals three times a day, 15-20 drops dissolved in a small amount of water. If necessary, the dose can be increased to 30. With an acute attack of tachycardia and severe pain in the chest area, you can drink 40-50 drops. Children can be given from 3 to 15 drops per day. You should not increase the dose yourself and experiment with this drug, as it can cause an overdose. Symptoms of an overdose are memory impairment, impaired coordination of movement, and the development of a depressed state. In this case, it is necessary to reduce the dose or stop taking the medicine altogether.

Is Corvalol banned? Can it be accepted?

For most people, Corvalol is considered a cure for all sores, but in fact it cannot be considered useful in the treatment of cardiovascular diseases. Its only action is the expansion of blood vessels and a sedative effect. Corvalol relieves certain symptoms that are caused by stress, not disease. The components of the drug (ethyl bromisovalerianate, ethyl alcohol, phenobarbital) accumulate in the body and cause poisoning of internal organs. With long-term use, a psychological and physiological dependence is formed (due to phenobarbital, a psychotropic substance that causes CNS depression and is a hard drug), which leads to poor sleep, anxiety, depression, and memory impairment. In many countries, Corvalol is prohibited, and in Russia it is released exclusively by prescription. So before taking this drug, think about whether you want to die from it?

Corvalol

Corvalol belongs to the group of sedative (sedative) drugs. In its composition, it contains phenobarbital, which is a psychotropic drug, isovaleric acid ester and oil from peppermint leaves. Due to the last component, not only the specific smell of Corvalol is provided, but also a reflex antispasmodic and vasodilating effect. A derivative obtained from valerian roots has a calming effect on the nervous system, and in large doses causes drowsiness. Thus, the action of Corvalol is due to its composition, which, in addition to the listed components, includes ethyl alcohol, sodium hydroxide and water.

Previously, there was only liquid Corvalol, drops of which had to be diluted with a certain volume of water. Currently, for the convenience of patients, Corvalol is produced in tablets for sublingual use.

Corvalol tablets are easy to use

Interestingly, this drug is distributed mainly on the territory of the Balkan Peninsula and in Russia. In other countries, they use a medicine that has a similar composition (valocordin). Phenobarbital, which is part of both drugs in some countries (USA, Lithuania) is equated to drugs and is prohibited for import.

Indications for use

The use of Corvalol is indicated for the following conditions:

changes in the function of the cardiovascular system associated with impaired neurohumoral regulation;
in the complex therapy of neuroses, as well as with increased excitability and irritability;
for taking Corvalol, indications include difficulty falling asleep due to increased anxiety;
tachycardia. associated with the influence of the sympathetic nervous system;
early stages of hypertension and slight spasm of the coronary arteries;
increased tone of the autonomic nervous system, accompanied by excitation;
spasms and increased peristalsis of the gastrointestinal tract.

How many drops of Corvalol to take in one case or another is determined by the doctor, but the average dosage is 20-40 drops three times a day.

Contraindications

Contraindications for taking Corvalol are individual allergic reactions and intolerance to the components of the drug, as well as severe somatic diseases accompanied by severe renal or hepatic insufficiency.

The calming effect of Corvalol has a beneficial effect on the cardiovascular system

Overdose

If an acute overdose of Corvalol occurs, then intestinal motility slows down, and this leads to constipation.

With prolonged use of the drug, chronic bromine poisoning is possible, which is manifested by depression and apathy, as well as damage to the mucous membranes (rhinitis, conjunctivitis), blood vessels (hemorrhagic diathesis) and the central nervous system (impaired speech, memory, attention, unsteady gait). Libido often decreases and impotence develops.

Side effects

Side effects usually do not occur with the correct dosage of the drug. However, sometimes you may experience dizziness, as well as drowsiness during the day. In some cases, drug dependence develops, and when it is canceled - abstinence.

Corvalol and alcohol

Often this drug is used to eliminate symptoms that have arisen after drinking a large amount of alcohol (hangover). These include heart palpitations. increased pressure, increased excitability. Due to the fact that Corvalol and alcohol have a sedative effect, when they are used together, an overdose and various side effects may develop.

Corvalol during pregnancy

It is possible to use Corvalol during pregnancy, as well as during breastfeeding, only according to strict indications. That is, if the expected benefit outweighs the harm likely to be inflicted on the child. This is due to the fact that phenobarbital, which is part of this medication, can negatively affect the condition and development of the baby's central nervous system, and also lead to intrauterine hypoxia.

Corvalol for children

Corvalol can be prescribed to children in special situations, while the dose should be reduced depending on age (one drop for one year of life). Interestingly, some doctors prescribe its use almost from birth, while others do not recommend taking it before 12 years. Since there is no consensus on this matter, it is worth listening to the opinion of your doctor, since only he has sufficient information about the child.

Corvalol is an indispensable drug in some situations when it is necessary to eliminate the symptoms of a severe shock or dysfunction of the nervous system. It is also suitable as a temporary measure for tachycardia and hypertension. However, with prolonged use, Corvalol often causes addiction and the development of side effects. Therefore, you should not self-medicate, but it is better to seek help from a specialist.

active substances: a-bromoisovaleric acid ethyl ester, phenobarbital, peppermint oil;

1 ml of solution (26 drops) contains: ethyl ester of α-bromoisovaleric acid 20 mg, phenobarbital 18.26 mg, mint oil 1.42 mg;

Excipients: ethyl alcohol (ethanol 96%), stabilizer (sodium isovalcriapat), purified water.

The medicinal product contains at least 56% (v/v) ethyl alcohol.

Pharmacological properties

Sleeping pills and sedatives. Barbiturates in combination with other agents.

ATC code N05C B02.

Combined drug.

The drug has a sedative or hypnotic effect depending on the dose.

Indications for use

As part of complex therapy as a symptomatic remedy for functional disorders of the nervous system (neurasthenia, sleep disorders).

The drug is intended for short-term use due to the risk of addiction and dependence.

Method of application and dosage

Doses and duration of administration are set by the doctor individually.

Adults Assign inside before meals 2-3 times a day for 15-30 drops, previously dissolved in a small amount of water.

The drug is intended for episodic short-term use due to the risk of addiction and dependence.

Side effect

From the nervous system: drowsiness, decreased concentration, slow reactions, impaired coordination of movements, dizziness, headache, nervousness, agitation, anxiety, confusion, increased motor activity, ataxia, depression of the central nervous system, sleep disturbance, insomnia, nightmares, mental disorders, hallucinations .

Sosidesrespiratory system: hypoventilation, apnea.

From the digestive system: nausea, vomiting, constipation with prolonged use - a violation of liver function.

From the side of the hematopoietic organs: megaloblastic anemia, thrombocytopenia, agranulocytosis.

From the sidecardiovascularsystems: bradycardia, low blood pressure, fainting.

From the side of the musculoskeletalWowdevice: with prolonged use of drugs containing phenobarbital, there is a risk of impaired osteogenesis. There have been reports of reduced bone mineral density, the development of osteopenia and osteoporosis, fractures in patients who have been taking phenobarbital for a long time. Others: blurred vision, allergic reactions (angioedema, skin rash, exfoliative dermatitis), fever, liver damage.

With prolonged use - drug dependence.

With prolonged use of large doses, the development of chronic bromine poisoning is possible, the manifestations of which are: depressive mood, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements.

After prolonged use, megaloblastic anemia may develop.

With the use of drugs containing phenobarbital, there have been reports of the development of life-threatening skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis).

In the event of adverse reactions, including those not listed in these instructions, you should stop taking the drug and consult a doctor.

Contraindications

Hypersensitivity to bromine or any component of the drug; renal and / or liver failure; porphyria; alcoholism, epilepsy, traumatic brain injury and other brain diseases with a decrease in the seizure threshold; pregnancy, lactation; children's age up to 18 years.

Overdose

Symptoms of chronic overdose: depression of the central nervous system, nystagmus, ataxia, lowering blood pressure, blood count disorders, agitation, chronic bromine intoxication (depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements).

With the development of symptoms of an overdose, it is necessary to stop taking the drug and consult a doctor.

Acute overdose of barbiturates is manifested in the depression of the functions of the central nervous system and the respiratory system: Cheyne-Stokes respiration, areflexia, oliguria, tachycardia, arterial hypotension, hypothermia and coma. Shock (apnea, circulatory collapse, respiratory arrest and death) may develop.

With the development of symptoms of acute overdose, it is necessary to maintain the vital functions of the body and conduct detoxification therapy, resuscitation may be required.

Precautionary measures

The drug contains at least 56% (v/v) ethyl alcohol, i.e. 255-510 mg of ethanol per single dose (15-30 drops), respectively. The drug should not be taken by patients with alcohol dependence, pregnant and breastfeeding women, children under 18 years of age, high-risk patients such as patients with liver disease and epilepsy.

Concomitant consumption of alcoholic beverages should be avoided.

Simultaneous alcohol intake increases the toxicity of phenobarbital.

It should be avoided prescribing the drug to patients with depressive disorders, suicidal tendencies, people with drug addiction.

Elderly and debilitated patients may respond to phenobarbital by developing marked agitation, depression, and confusion.

With prolonged use, accumulation of bromine in the body and the development of intoxications are possible.

Phenobarbital can cause the development of addiction, mental and physical dependence. When addiction (tolerance) to phenobarbital develops, the dose required to maintain the same level of effect increases. Abrupt discontinuation of phenobarbital after long-term use in a dependent individual may lead to withdrawal symptoms.

In case of signs of intoxication, addiction (tolerance) or dependence, the patient should immediately consult a doctor. Signs of chronic intoxication include confusion, decreased criticism, irritability, insomnia, and somatic complaints.

Caution should be exercised when prescribing phenobarbital to patients with acute or chronic pain because paradoxical arousal may develop and important clinical symptoms may be masked.

There have been reports of the development of life-threatening skin reactions (Stevens-Johnson syndrome and toxic epidermal necrolysis) with the use of drugs containing phenobarbital. The best results in the treatment of Stevens-Johnson syndrome or toxic epidermal necrolysis have been obtained with early diagnosis and immediate discontinuation of the suspected drug. These patients should no longer resume the use of Corvalol®.

Use during pregnancy orbreastfeeding

Taking phenobarbital during pregnancy can cause fetal abnormalities. After oral administration, phenobarbital crosses the placental barrier and is distributed to all tissues of the fetus, high concentrations are determined in the placenta, liver and brain. If phenobarbital was taken during pregnancy or if pregnancy occurred while taking phenobarbital, the patient should be informed of the potential hazard to the fetus. When taking phenobarbital to a nursing mother, small amounts of phenobarbital are excreted in breast milk.

The drug Corvalol is contraindicated in pregnant women and women who are breastfeeding.

Children

The drug is contraindicated in children and adolescents under the age of 18 years.

The ability to influence the reaction rate when driving andwhether work with other mechanisms

The drug contains ethyl alcohol, phenobarbital and ethyl ester of α-bromisovaleric acid, therefore, patients taking Corvalol® are contraindicated in driving vehicles and engaging in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Interaction with other drugs

Phenobarbital induces liver enzymes and therefore may accelerate the metabolism of certain drugs that are metabolized by these enzymes (for example, coumarin derivatives, antibacterials and sulfonamides).

When taken simultaneously with coumarin derivatives, lamotrigine, thyroid hormones, doxycycline, chloramphenicol, antifungal drugs (azole type), griseofulvin, glucocorticoids or oral contraceptives with Corvalol®, adverse reactions and interactions may occur due to the phenobarbital contained in the preparation.

Women taking phenobarbital should be offered non-hormonal methods of contraception.

The toxicity of pharmaceutical preparations containing methotrexate is increasing.

The effect of phenobarbital on the metabolism of phenytoin is unpredictable, the concentrations of phenytoin and phenobarbital in the blood should be monitored if these drugs are prescribed simultaneously.

Sodium valproate and valproic acid inhibit the metabolism of phenobarbital.

Interactions associated with the presence of ethyl alcohol in the composition: it is necessary to avoid co-administration of drugs that cause a disulfiram-like reaction (feeling of heat, redness of the skin, vomiting, tachycardia) when taken together with alcohol (disulfiram, cefamandol, cefoperazone, latamoxef, chloramphenicol, chlorpropamide, glibenclamide, glipizide, tolbutamide, griseofulvin, nitro-5-imidazole derivatives (metronidazole, ornidazole, tinidazole), ketoconazole, procarbazip).

It is necessary to avoid the simultaneous use of other drugs containing ethyl alcohol.

PJSC Farmak. Ukraine, 04080, Kiev, st. Frunze, 63.

An overdose of Corvalol is an intoxication of the body with this drug and its constituent components. And if most patients can endure such poisoning relatively easily, then some may have serious complications (including death).

In general, an overdose of Corvalol is terrible only for those people who are allergic to this substance and the accompanying components of the drug. And more often than not, an overdose is caused not by chance, but by the patient taking a high dose of the drug on purpose to enhance its effect.

In this article, we will talk in detail about how dangerous an overdose of Corvalol is and what to do if its first signs appear. We will also talk about what dosage of this drug is normal.

Corvalol is almost the most popular drug in the CIS countries. About 150 million packages of this medicine are purchased annually in the CIS countries. Far from always buying it for an existing disease, in the vast majority of cases, "Corvalol" is taken "just in case."

Corvalol does not directly affect the heart, although many patients think otherwise. In fact, this drug has a sedative effect that calms the patient's nervous system.

Samo the medicine consists of the following components:

ethyl ester of a-bromoisovaleric acid;
filtered water;
sodium hydroxide;
phenobarbital;
peppermint oil.

A serious drawback of such a drug is the addiction of the patient. Moreover, the patient not only starts taking Corvalol daily, but also increases the dose in the hope of a more effective and lasting effect of the drug.

Purpose and benefits of application

The constituent components of Corvalol have a pronounced effect on many human diseases (mainly neurological). So corvalol is useful to deal with the following problems:

Disorders of the cardiovascular system (arrhythmias, tachycardia).
Sleeplessness and irritability.
Hypochondria and suspiciousness.
Vegetovascular dystonia.
With a low persistent rise in blood pressure.

It is worth noting that usually this medicine is not prescribed as an independent treatment for the diseases listed above, but only as an auxiliary treatment. Corvalol enhances the overall effect of therapy, and in case of an acute onset of the disease (for example, sinus tachycardia or a panic attack), it is a means for quickly relieving an attack.

Who prescribes the course of treatment?

Despite the fact that this medicine can be purchased without a prescription, you should still consult your doctor before purchasing it. If the medicine is required for the treatment of cardiovascular diseases, then you need to consult with a cardiologist or vascular surgeon.

In the presence of neurological diseases (VSD, hypochondria, panic attacks), before buying the drug, you should consult a psychotherapist or neurologist. In case of insomnia, consultation should be carried out either with a general practitioner or with a neurologist.

It is important to understand that pharmacists in a pharmacy are not authorized to prescribe medication to clients. Therefore, it is dangerous to purchase Corvalol based on the opinion of a pharmacist.

Harm from taking Corvalol

In addition to the previously described disadvantage in the form of addiction, Corvalol has other significant disadvantages. So the combination of phenobarbital with an alcohol solution depresses the functions of the central nervous system and disrupts the coordination of movements.

Intoxication with these components of Corvalol, which occurs during an overdose, can even cause death. The critical dose that can already cause death is half a standard bottle of Corvalol.

When interacting with tranquilizers and other sedatives, complications can also occur. So phenobarbital, which is a component of Corvalol, upon contact with the listed drugs, significantly enhances their effect.

As a result, the effect of sedatives increases so much that the patient becomes lethargic, sleepy and inhibited. Even sopor and deep pathological sleep are possible.

What is obvious, all the listed complications of taking Corvalol are somehow connected with its incorrect use. A moderately increased dosage or combination of the drug with its analogues can lead to serious consequences, sometimes even causing a fatal outcome (especially in elderly patients).

Norm: how many drops of Corvalol can you drink?

The drug is approved for use for those patients who are over 18 years old. The standard dosage of the drug applies to all ages, starting from 18 years. That is, simply put, it is universal.

drug without fear can be taken in the following doses:

For neurological diseases: the dose is 15-20 drops, no more than three times a day.
In diseases of the cardiovascular system: you can drink no more than 40 drops per day, no more than three times a day.
For the prevention of panic attacks: you can take 10-15 drops per day.

In some cases, the dose can be slightly increased, but only after a mandatory consultation with the doctor. Ignoring this rule entails serious consequences (including death).

How many days can I drink Corvalol?

The consequences of long-term use of Corvalol have been studied quite well and are currently considered harmless. The main consequences of long-term use are only dry mouth and psychological dependence on the drug.

The drug does not have a toxic effect on all internal organs in general, and on the kidneys with the liver in particular. Only in elderly patients can chronic bromine intoxication be observed (it is contained in phenobarbital, an integral component of Corvalol).

This condition rarely becomes a serious independent disease. Typically, bromine intoxication is characterized by drowsiness, depression and apathy. If these symptoms appear, the drug should be temporarily discontinued and contact your doctor.

Lethal dosage

The maximum dose of the drug at which the body can cope with the load and remove excess is 150 drops. However, in those patients who have chronic renal or hepatic insufficiency, this dose may be lethal.

The consequences of taking a dose exceeding 150 drops are severe poisoning and death with a high degree of probability (even in healthy people). It is estimated that lethal dosage is 0.1-0.3 grams per 1 kilogram of body weight patient. On average, this is 20 grams of medicine.

The causes of mild and severe corvalol poisoning are not as simple as it seems at first glance. The main component contained in the drug is absolutely safe in recommended doses, but in high doses it is fatal. To be more precise, we are talking about phenobarbital.

In high doses, it strongly inhibits psychomotor reactions and causes coordination disorders. In ultra-high doses, it disrupts the conduction of the nerves of the heart, causing it to stop.

Moreover, this component can be dangerous in normal doses, but only in some cases. Namely:

with the concomitant use of alcoholic beverages;
when combined with pure alcohol;
when used with tranquilizers;
when used with sedative drugs;
when used with antiemetic drugs.

Why is an overdose dangerous?

Poisoning with this drug due to an overdose is fraught with serious health consequences and, in more rare cases, death. An overdose is especially dangerous in cases where alcohol was taken the day before.

Alcohol is a catalyst for the components of Corvalol, which only aggravates the situation in case of an overdose. An excessive dose of Corvalol and drunk alcohol often cause collapse, severe coma and death.

Insidious poisoning with this drug is also because the patient is in deep sedation, similar to complete apathy and stupor. As a result, the patient does not even realize that he is in a critical condition, so he cannot orient himself in time and call an ambulance.

Symptoms of an overdose of Corvalol

The symptoms of acute intoxication with Corvalol are quite expressive, so many doctors, even without clinical blood tests, will be able to accurately diagnose.

Signs of such intoxication at its simplest, the following:

drowsiness;
general weakness;
lethargy and distraction;
a slight decrease in muscle strength;
Difficulties in pronouncing complex sentences.

Symptoms of moderate intoxication:

prolonged pathological sleep (it is very difficult to wake the patient up);
salivation;
severe muscle weakness;
convulsions;
lack of urge to urinate;
pupil dilation.

Symptoms of severe poisoning:

lack of consciousness;
coma;
respiratory failure (patient breathes shallow, often);
drop in blood pressure;
wheezing in the lungs;
tachycardia with a heart rate exceeding 130 beats;
cyanosis of the skin.

The danger of Corvalol (video)

First aid and treatment

First aid is possible only with a mild overdose of Corvalol. In this case, it is necessary to carry out a thorough gastric lavage of the patient as soon as possible. To do this, you need to give him about 20 grams of activated charcoal and a liter of warm liquid.

A laxative (salt-based) and cleansing enemas will be useful. After the bowel cleansing, the patient should be given an enveloping drink.

In case of moderate and severe overdose, you need to call an ambulance as soon as possible. Attempts to clear the stomach and intestines of the patient on their own are futile, since he is not able to take a sip.

Which doctor should I contact?

Corvalol intoxication can be treated by a general practitioner, toxicologist and gastroenterologist. Therefore, when calling an ambulance, you need to be guided by some rules.

So the dispatcher should be asked to send a highly specialized team of doctors (therapist, toxicologist or gastroenterologist). Also, the dispatcher should be informed that not a linear team is required, but an intensive care team.

The fact is that linear ambulance crews do not have special equipment on board to restore the pressure and heart rhythm of the patient. Only specialized resuscitation teams (so-called reanimobiles) have such equipment.